t (3; 22)(q21;q12) in a pregnant woman with two abortions and postnatal death of one offspring
نویسندگان
چکیده
background: carriers of translocations may have an increased risk of an unbalanced progeny due to imbalances and delays in meiosis. case: a 24-year-old pregnant iranian female was referred to the genetic department of yazd clinical and research centre for infertility because of her pregnancy history. she had three previous pregnancies, two of which ended in abortion. the one live born infant was a girl who had multiple abnormalities and died when she was 11 days old. the cytogenetic analysis showed that the woman is a carrier of chromosomal translocation 46, xx, t (3; 22) (q21; q12), while her husband’s karyotype was found to be normal. the karyotype of her mother showed the same translocation. the risk of further miscarriages was high, and the proband was monitored closely during her pregnancy. after nine months of pregnancy, a normal baby girl weighted 3460 gr was delivered by caesarean section. three hours after birth, the baby suffered from jaundice and respiratory distress. the baby’s phenotype was normal. she received routine treatment successfully and after 15 days she was discharged from the hospital in a good condition. the baby’s karyotype showed the same translocation as her mother and grandmother. conclusion: to our knowledge, no translocation with such breakpoints t (3; 22) (q21; q12) has been described previously in the women with rpl.
منابع مشابه
Preoperative Emboli in a Pregnant Woman with Myxoma
The left atrium is the most common location of myxomas, which are benign tumors. Only a few cases of myxomas in pregnancies have been reported. Our thorough medical literature search showed only 17 reported cases in the course of pregnancy. Myxomas during pregnancy and in the preterm period constitute a serious phenomenon that can mimic an early sign of a life-threatening pathology like severe ...
متن کاملa synchronic and diachronic approach to the change route of address terms in the two recent centuries of persian language
terms of address as an important linguistics items provide valuable information about the interlocutors, their relationship and their circumstances. this study was done to investigate the change route of persian address terms in the two recent centuries including three historical periods of qajar, pahlavi and after the islamic revolution. data were extracted from a corpus consisting 24 novels w...
15 صفحه اولManagement of Anesthesia During Splenectomy and Cholecystectomy in a Pregnant Woman With Hereditary Spherocytosis
Hereditary spherocytosis (HS) is a familial hemolytic disorder with intracorpuscular mechanism that characterized by the production of red blood cells with sphere-like shape prone to hemolysis and can lead to hemolytic anemia, splenomegaly, jaundice and gallstones. One of the main reasons for referring these patients to the operating room is splenectomy and cholecystectomy to treat the complica...
متن کاملa comparison of teachers and supervisors, with respect to teacher efficacy and reflection
supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...
15 صفحه اولمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
international journal of reproductive biomedicineجلد ۵، شماره ۲، صفحات ۷۳-۰
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023